Browse articles from EyeWorld.org on the topic of the cornea. EyeWorld is the award-winning member publication of ASCRS. The magazine provides news and updates from the Society as well as clinical features in the areas of cataract, refractive, cornea, glaucoma, and practice management. It publishes quarterly with editorial direction from its medical editorial board and staff.
The articles in the Cornea section represent a challenge to corneal specialists to develop the centers necessary to treat complex conditions or refer patients to providers who have. “Reading them made me feel a renewed energy and commitment to patient care, and I hope you feel the same,” said Cornea Editor Julie Schallhorn, MD.
Identifying and treating patients with limbal stem cell dysfunction or deficiency can be a challenging process. Several physicians discussed how they handle these patients, including which techniques are available for mild to more severe disease.
➤ Phase 3 clinical trial for water-free dry eye cyclosporine drop ➤ Phase 2b results for drug-eluting contact lens for glaucoma ➤ Dosing continues for Phase 1/2 trial evaluating gene therapy for X-linked retinoschisis ➤ Higher dose, extended wet AMD treatment non-inferior to standard of care ➤ Study: AI detects severe retinopathy of prematurity with 100% accuracy ➤ Complimentary access to video journal ➤ ASCRS news and events
Peripheral ulcerative keratitis is an inflammatory condition that typically affects the peripheral cornea leading to corneal thinning and corneal melt. It is commonly associated with an underlying autoimmune process. Two physicians shared their experiences with diagnosis and management of the condition.
➤ Enrollment complete in Phase 2 study for drug targeting endocannabinoid system for IOP lowering ➤ Dosing complete for Phase 1/2 trial evaluating a gene therapy for Stargardt disease ➤ Pre-Phase 3 Type B meeting held with FDA by company focused on retinitis pigmentosa ➤ Updates from several late-stage clinical trials ➤ New company launches to pioneer nonviral gene therapies ➤ ASCRS news and events
➤ FDA approves new excimer laser technology ➤ Phase 3 trial to evaluate phentolamine for treatment of decreased visual acuity ➤ Phase 2 trial of investigational dry eye drug sees effect on signs and symptoms ➤ Study has new findings to promote corneal healing ➤ ASCRS news and events
The topic of ocular allergy and associated conjunctivitis is broad, ranging from seasonal to perennial, acute/episodic to chronic. EyeWorld asked an ocular surface specialist and an ocular allergist/immunologist to provide an overview on the topic.
➤ Positive topline results in Phase 2a trial for treatment of MGD in patients with Demodex ➤ First patient visit in Phase 2b trial evaluating anti-TNFα for dry eye disease ➤ Smart contact lens makes progress ➤ Asset transition ➤ ASCRS news and events
In this article, two ophthalmologists spoke about what they look for when diagnosing neurotrophic keratitis and treatment options.
“The theme of this issue, ‘Lessons Learned,’ acknowledges that a lot of the time, we just don’t get it right,” said Cornea Editor Julie Schallhorn, MD, in her introduction to the section.