Browse articles from EyeWorld.org related to SMILE. EyeWorld is the award-winning member publication of ASCRS. The magazine provides news and updates from the Society as well as clinical features in the areas of cataract, refractive, cornea, glaucoma, and practice management. It publishes quarterly with editorial direction from its medical editorial board and staff.

The penetration of refractive procedures in various markets

When it comes to refractive procedures, there are many options available. Several physicians discussed what they’re using and the options available, notably market penetration of the Implantable Collamer Lens (ICL, STAAR Surgical) and SMILE in different areas and how this has changed over the years.

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EyeWorld Weekly, January 19, 2024

➤ FDA approves updated femtosecond laser for refractive surgery ➤ Positive topline results from Phase 3, first-in-class dry eye disease studies ➤ Rare Disease Designation granted for investigational gene therapy ➤ Positive interim data for investigational Stargardt disease treatment ➤ First patient dosed in Phase 2 trial for DME treatment ➤ Research program established to investigate whole eye transplant ➤ ASCRS news and events

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EyeWorld Weekly, October 27, 2023

➤ Editorial statement on the nomenclature for refractive lenticule extraction procedure ➤ First patient dosed in Phase 1/2 trial evaluating allogenic cell therapy for corneal edema ➤ IND granted to company investigating therapy for geographic atrophy ➤ Licensing agreement to develop neuroprotective drug ➤ Retinal imaging test detects increased risk for type of dementia ➤ ASCRS news and events

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EyeWorld Weekly, September 22, 2023

➤ First AI foundation model in ophthalmology ➤ 24-month topline data from Phase 3 geographic atrophy therapy ➤ Positive data from Phase 1/2 trial for retinitis pigmentosa, Leber congenital amaurosis treatment ➤ FDA clearance granted for portable retinal imaging system ➤ ASCRS news and events

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EyeWorld Weekly, May 26, 2023

➤ FDA approves dry eye drop targeting tear evaporation ➤ Topline results from Phase 3 trial of eye drops for DME ➤ Investigational intravitreal gene therapy program introduced for geographic atrophy ➤ Phase 1 study for periocular drug for wet AMD and DME begins ➤ Commercial rights for uveitis treatment acquired ➤ ASCRS news and events

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EyeWorld Weekly, March 31, 2023

➤ Patient enrollment complete for sustained release AMD therapy trial ➤ First patient dosed with corneal endothelial cell substitute ➤ First patient dosed in RNAi therapy for wet and dry AMD ➤ Study: early signs of corneal graft rejection reversed with steroid nanoparticle ➤ Company announces anti-VEGF market tracker ➤ ASCRS news and events

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Read more about the article A discussion on SMILE
Day 1 postop photo of SMILE Source: Audrey Talley Rostov, MD

A discussion on SMILE

Two surgeons shared how they have incorporated small incision lenticule extraction (SMILE) into practice, what they’ve learned, and issues that may occur. They also addressed advancements and future innovation in the space.

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EyeWorld Weekly, November 11, 2022

➤ Phase 1/2a results for suprachoroidal wet AMD treatment ➤ Enrollment complete for two Phase 2 trials investigating dry eye therapies disease ➤ Phase 2b study for drug-eluting contact lens begins ➤ Healthcare company acquires biopharmaceutical company developing ophthalmic treatments ➤ Development and commercialization licensing agreement ➤ ASOA podcast features dry eye info for the practice ➤ ASCRS news and events

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EyeWorld Weekly, March 4, 2022

➤ FDA approves first drug-eluting contact lens ➤ FDA accepts 510(k) submission for new femto-phaco device ➤ Phase 2 study begins to evaluate an immunomodulatory agent for dry eye ➤ Licensing agreement for optic nerve-protective therapy ➤ Phase 3 study to evaluate protein replacement solution for dry eye ➤ Study: Impact of age on SMILE outcomes ➤ ASCRS news and events

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Feeling the excitement build

Vance Thompson, MD, Refractive editor, discusses highlights of the section and how this issue is “a wonderful invitation to our extended family in ophthalmology and a representation of important topics that will be represented at the Annual Meeting.”

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