June 2019


Studying intracameral prophylaxis

While no FDA trial has taken place in the U.S., there’s a plethora of evidence that intracameral injections are effective in forestalling postoperative cataract infection.
•In Europe, the ESCRS trial comparing no drops or topical drops to intracameral cefuroxime injections or intracameral injections plus drops showed an overwhelming reduction in the risk of endophthalmitis, Dr. Donnenfeld noted. “There were approximately 14,000 patients enrolled, and there was a 5-fold reduction in endophthalmitis with use of intracameral cefuroxime,” he said.
•Kaiser Permanente did a study of intracameral moxifloxacin versus topical. It showed a statistically significant reduction in endophthalmitis with the injections, Dr. Lindstrom noted.
•Several prospective clinical trials studied safety and efficacy of intracameral moxifloxacin in Brazil and at the Aravind Eye Center in India and highlighted the effectiveness of this approach, Dr. Lindstrom said.

Studying intracameral prophylaxis Studying intracameral prophylaxis
Ophthalmology News - EyeWorld Magazine
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