March 2020

ASCRS NEWS

EyeWorld Journal Club
Prospective randomized comparative trial: Visual performance comparison of two enhanced depth of focus IOLs – Symfony and IC-8


by Merita Schojai, MD, Tim Schultz, MD, Corinna Jerke, MS-V, Jörg Böcker, Dipl Ing, H. Burkhard Dick, MD

J Cataract Refract Surg. 2020;46(3):388–396.
• Purpose: To compare the visual acuity and satisfaction outcomes of two different concepts of enhanced depth of focus intraocular lenses (EDOF IOLs).
• Setting: University Eye Hospital Bochum, Germany
• Design: Prospective randomized comparative clinical trial
• Methods: This study included a sample of 76 eyes of 38 patients undergoing cataract surgery with the implantation of two different EDOF concepts. In the first group (IC-8 group) a monofocal one-piece Tecnis ZCB00 IOL (Johnson & Johnson Vision) was implanted in the dominant eye and an IC-8 IOL (AcuFocus) was implanted in the non-dominant eye. In the second group (Symfony group) a Tecnis Symfony IOL (Johnson & Johnson Vision) was implanted in both eyes. The target refraction of the dominant eye was emmetropia and slight myopia (mini-monovision; –0.75 D) in the non-dominant eye. Visual and refractive outcomes and patient satisfaction rates were evaluated 3 months after surgery.
• Results: In both groups no intra- or postoperative complications occurred. The target refraction was reached in both groups without statistically significant differences. The uncorrected distance visual acuity (UDVA, photopic and mesopic light conditions) was excellent in both groups with statistically significant better results in the IC-8 group (logMAR; IC-8 group –0.1 ± 0.07, Symfony group 0.07 ± 0.1, p value 0.02 [photopic]; IC-8 group 0.12 ± 0.09, Symfony group 0.22 ± 0.1, p value <0.01 [mesopic]). Binocular uncorrected intermediate visual acuity (UIVA) and uncorrected near visual acuity (UNVA) were also good in both groups without significant differences (UIVA IC-8 group 0.01 ± 0.07, Symfony group –0.01 ± 0.08, p value 0.35; UNVA IC-8 group 0.14 ± 0.11, Symfony group 0.09 ± 0.08, p value 0.14). Subjective satisfaction was high in both groups.
• Conclusion: Both EDOF IOLs provided a very good UDVA with superior results in the IC-8 group, good UIVA and UNVA under photopic light conditions. Subjective patient satisfaction was higher in the IC-8 group.

Prospective randomized comparative trial: Visual performance comparison of two enhanced depth of focus IOLs – Symfony and IC-8 Prospective randomized comparative trial: Visual performance comparison of two enhanced depth of focus IOLs
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2020-03-02T15:48:39Z
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