EW Weekly, December 4, 2020

- Survey: Public lacks understanding of cataract treatment options
- Proof-of-concept study for epigenetic reprogramming in the eye
- Second Phase 3 study launched for first-in-class dry eye drug
- Pre-IND meeting for multi-dose latanoprost formulation
- Company acquires investigational gene therapy
- CMS released CY 2021 MPFS Final Rule
- ASCRS launches Journal Club
- Introducing ASCRS’ new podcast
- 20/Happy in 2020: ASCRS continues master class
- Research highlights
- Product news
- For the first time, researchers from the University of Connecticut have isolated and studied, using single-cell RNA sequence analysis, non-myelinating corneal Schwann cells that ensheathe stromal axons. According to an article published by the university’s news website, gaining a better understanding of these cells could further knowledge of corneal pain, healing, and nerve regeneration. Researchers in the article described how a better understanding of gene expression of these cells, even within different areas of the cornea, could help advance treatments for chronic dry eye and post-LASIK dry eye. The study is published in the Journal of Neuroscience Research.
- A single-practice study evaluated endothelial cell density and cell morphology after phacoemulsification cataract surgery and Kahook Dual Blade (New World Medical) or phaco and iStent (Glaukos). The study included 21 patients who had phaco+KDB in one eye and phaco+iStent in the other. Both procedures were associated with postop endothelial cell loss, according to the authors, but the eye that received iStent saw more loss (–9% change from baseline compared to –3.4% change from baseline in the Kahook eye). The study authors wrote that the clinical findings of this research are unknown and future studies that look at the long-term effects of glaucoma procedures on corneal health and endothelial cell density are merited. The research is published in the journal Clinical Ophthalmology.
This issue of EyeWorld Weekly was edited by Stacy Jablonski and Vanessa Caceres.
EyeWorld Weekly (ISSN 1089-0319), a digital publication of the American Society of Cataract and Refractive Surgery (ASCRS), is published every Friday, distributed by email, and posted live on Friday.
Medical Editors: Eric Donnenfeld, MD, Chief Medical Editor; Rosa Braga-Mele, MD, Cataract Editor; Clara Chan, MD, Cornea Editor; Nathan Radcliffe, MD, Glaucoma Editor; and Vance Thompson, MD, Refractive Editor
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