EW Weekly, June 12, 2020

- Objective sign for treatment of dry eye disease
- FDA approves updated Beovu label
- Noninvasive retinal imager receives FDA approval
- ASCRS and IJCAHPO Technicians & Nurses Program virtual broadcast
- Research highlights
- Product news
- Post-hoc secondary analysis of two randomized clinical trials (the Ocular Hypertension Treatment Study and the European Glaucoma Prevention Study) sought to evaluate whether long-term intraocular pressure variability could improve prediction of patients progressing from untreated ocular hypertension to primary open-angle glaucoma (POAG). The research included 709 patients and ultimately found that “adding intraocular pressure SD, maximum, range, or coefficient of variation to a model that included mean follow-up intraocular pressure and baseline factors did not significantly increase predictive accuracy.” This, according to Mae Gordon, PhD, and coresearchers, suggests that including long-term IOP variability is not likely to improve prediction models from ocular hypertension to POAG. The research is published in JAMA Ophthalmology.
- A study assessing the value of intraoperative OCT in DMEK surgery found the technology to be useful in graft orientation, appositioning, and helping to reduce surgical time. According to the study published in Cornea by Marc Muijzer, BSc, and coinvestigators, of the 38 cases analyzed, some included prolonged over pressurization of the globe while others did not. The researchers found intraoperative OCT provided valuable information for surgical decision-making in 43% of cases.
- A study that looked at the effect of low-dose atropine on ocular biometrics found that there was no clinical effect on corneal power or lens power at the doses (0.05%, 0.025%, and 0.01%) evaluated. The research, led by Li Fen-Fen, MD, and colleagues, showed that the effect on myopia mainly reduced axial length elongation. The study published in Ophthalmology was double-blinded, randomized, placebo-controlled, and included 383 children 4–12 years old.
- A literature review assessed the outcomes and safety of IOL implantation without zonular support. Forty-five studies (out of 734) were included in the analysis, three with level II evidence and 42 with level III evidence. The studies included eight types of IOL fixation techniques: anterior chamber IOL, iris-claw IOL, retropupillary iris-claw IOL, 10-0 polypropylene iris-sutured posterior chamber IOL (PCIOL), 10-0 polypropylene scleral-sutured PCIOL, 8-0 polypropylene scleral-sutured PCIOL, CV-8 polytetrafluoroethylene, and intrascleral haptic fixation. Joanne Shen, MD, and coresearchers concluded that no one technique showed superiority, with various techniques having similar visual acuity and safety outcomes. The authors acknowledged that each technique has its own risk of complications and wrote that surgeons need to educate patients on the importance of follow-up to monitor the results of these techniques. They also stated that large, prospective studies are needed to assess long-term complications.
- BVI launched CryoTreq, a single-use cryo-surgery device for treating retinal tears and detachments, in Europe.
- The FDA approved Bausch + Lomb’s INFUSE daily disposable contact lenses that include a new material (kalifilcon A) and other technologies designed to address contact lens dryness.
- M&S Technologies launched web-based, at-home vision testing/screening. The test includes e-ETDRS, ATS/HOTV, and screening protocols.
- Implandata launched its web-based, remote IOP monitoring EYEMATE IOP-Tracking Service in Europe, allowing patients to collect IOP measurements at home. EYEMATE is CE marked and is in the approval process as a Breakthrough Device with the FDA.
This issue of EyeWorld Weekly was edited by Stacy Jablonski and Vanessa Caceres.
EyeWorld Weekly (ISSN 1089-0319), a digital publication of the American Society of Cataract and Refractive Surgery (ASCRS), is published every Friday, distributed by email, and posted live on Friday.
Medical Editors: Eric Donnenfeld, MD, Chief Medical Editor; Rosa Braga-Mele, MD, Cataract Editor; Clara Chan, MD, Cornea Editor; Nathan Radcliffe, MD, Glaucoma Editor; and Vance Thompson, MD, Refractive Editor
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