EW Weekly, January 17, 2020

- Eye care business from Allergan to be integrated into AbbVie
- Phase 1b results: Tolerability and IOP lowering among findings with AKB-9778
- First patient dosed with ALY688 for dry eye
- Results announced from OPTIC Phase 1 trial of ADVM-022 gene therapy for AMD
- Pilot study results announced with visual prosthesis for late-stage RP
- New CPT codes for Notal Vision home-based OCT technology
- CE mark given for STAAR EVO ICL in post-cataract patients
- Make your plans for the 2020 ASCRS Annual Meeting
- A family history of keratoconus, allergy, asthma, and eczema were the largest risk factors for keratoconus in a systematic review and meta-analysis, according to Hassan Hashemi, MD, and coresearchers. Their review retrieved 3,996 articles and analyzed 29 of them. Among the 29 articles, there were more than 7.1 million participants from 15 countries. Prevalence was 1.38 per 1,000 among the whole population. Prevalence among men was 20.6 per 1,000 and 18.33 per 1,000 in women in studies that reported sex. The odds ratios for eye rubbing, family history of keratoconus, allergy, asthma, and eczema were 3.09, 6.42, 1.42, 1.94, and 2.95, respectively. The study appears in Cornea.
- There was a limited refractive predictability with the use of wavefront-guided customized treatment with excimer laser in highly aberrated corneas, reported Rana Hanna, MD, and coresearchers. Their retrospective, consecutive, noncomparative case series used the Amaris excimer laser and ORK-CAM software (both Schwind eye-tech-solutions) to calculate the ablation profile. Included eyes were post-refractive and keratoplasty procedures or had high irregular astigmatism with significant high order aberrations (HOAs) that had wavefront-guided customized treatment. A total of 55 treatments in 51 eyes of 35 patients were included. The postop uncorrected distance visual acuity was 0.2 logMAR or better in 72% of eyes. Postop residual manifest refraction spherical equivalent was ±0.50 D in 56% of eyes; 11% lost one line or more of corrected distance visual acuity. Post-hyperopic treatment was associated with a higher rate of refractive surprises. Eyes with preop coma-like aberrations were more likely to benefit from a reduction in HOAs. The study appears in the Journal of Cataract & Refractive Surgery.
This issue of EyeWorld Weekly was edited by Stacy Jablonski and Vanessa Caceres.
EyeWorld Weekly (ISSN 1089-0319), a digital publication of the American Society of Cataract and Refractive Surgery (ASCRS), is published every Friday, distributed by email, and posted live on Friday.
Medical Editors: Eric Donnenfeld, MD, Chief Medical Editor; Rosa Braga-Mele, MD, Cataract Editor; Clara Chan, MD, Cornea Editor; Nathan Radcliffe, MD, Glaucoma Editor; and Vance Thompson, MD, Refractive Editor
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