January-February 2020

ASCRS NEWS

Assessment of the accuracy of new and updated IOL power calculation formulas in 10,930 eyes from the UK National Health Service


by Kieren Darcy, BM MRCS(Eng), David Gunn, MBBS (Hons I), Shokufeh Tavassoli, MBBS, John Sparrow, D Phil, Jack Kane, MBBS

J Cataract Refract Surg. 2020;46(1):2–7.

• Purpose: To compare the accuracy of new/updated methods of IOL power calculation (Kane, Hill 2.0, Holladay 2 with new axial length adjustment) to that of established methods (Barrett Universal 2, Olsen, Haigis, Holladay 1, Hoffer Q, and SRK/T).

• Setting: Bristol Eye Hospital, University Hospitals Bristol NHS, Foundation Trust, Bristol, U.K.

• Design: Retrospective consecutive case series

• Methods: Data from patients having uncomplicated cataract surgery with insertion of one of four IOL types was included. Optimized lens constants were used to calculate the predicted refraction of each formula for each patient. This was compared with the actual refractive outcome to give the prediction error. Subgroup analysis occurred based on axial length and IOL type.

• Results: The study included 10,930 eyes of 10,930 patients with the Kane formula having the lowest mean absolute prediction error (MAE), which was statistically significant (p<0.001 in all cases) followed by the Hill 2.0, Olsen, Holladay 2, Barrett Universal 2, Holladay 1, SRK/T, Haigis, and Hoffer Q. The percentage of eyes within ±0.5 diopters of predicted was Kane 72%, Hill 2.0 71.2%, Olsen 70.6%, Holladay 2 71%, Barrett 2 70.7%, SRK/T 69.1%, Haigis 69%, and Hoffer Q 68.1%. The Kane had the lowest MAE for short, medium, and long axial length subgroups and for each IOL type assessed. The updated versions of the Holladay 2 and Hill 2.0 have resulted in improved accuracy.

• Conclusions: Overall and in each axial length subgroup the Kane formula was more accurate than the other formulas.

Assessment of the accuracy of new and updated IOL power calculation formulas in 10,930 eyes from the UK National Health Service Assessment of the accuracy of new and updated IOL power calculation formulas in 10,930 eyes from the UK
Ophthalmology News - EyeWorld Magazine
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2020-01-13T12:57:34Z
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