April 2009




Mydriatic cocktail a safe, economical, timesaving alternative


Recent study results show that the mydriatic cocktail regimen delivered with a wick is a useful, economical, and timesaving compared to the conventional method of pre-op mydriasis using topical drops.

Dr. Sabyasachi Sengupta, Jawaharlal Institute of Post-graduate Medical Education and Research (JIPMER), Pondicherry, India, and his colleagues investigated the efficacy of a standardized wick soaked in a mydriatic cocktail regimen and compared it with the pre-existing regimen of topical dilating drops in a prospective, two armed, randomized, double blind, parallel assignment efficacy study published in the March issue of Eye.

For the study, they dilated 150 eyes of 150 patients using the specially prepared mydriatic cocktail regimen for a minute with a Weck cell sponge and placed in the lower fornix with sterile forceps. The control group comprised 75 eyes of 75 patients dilated using the conventional mydriatic regimen of topical flurbiprofen eye drops applied every 15 minutes.

They measured the mydriasis at 15, 30, and 45 minutes after instillation using a pupillometer under scotopic conditions.

Dr. Sengupta said there was a statistically significant difference (P< 0.001) in dilation achieved at the end of 45 minutes in both groups. There was also a significant difference of 1mm of dilation between the two groups after nucleus delivery (P<0.001), and a difference of 1.41mm after intraocular lens (IOL) implantation, which was statistically significant (P<0.001).

Reported by: EyeWorld News Services

Mydriatic cocktail a safe, economical, timesaving alternative Mydriatic cocktail a safe, economical, timesaving alternative
Ophthalmology News - EyeWorld Magazine
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