February 2008

 

CATARACT/ IOL

 

Interocular axial length difference and age-related cataract


   

A recent study, published in the January issue of the Journal of Cataract and Refractive Surgery found the increase in axial length in patients with age-related cataract to be associated with greater asymmetry between eyes and more postoperative anisometropia, especially in eyes with an axial length greater than 28.0 mm.

Madhavan S. Rajan M.D., FRCOphth, FCRS, Moorfields Eye Hospital, London, U.K., and colleagues analyzed the preoperative biometry and postoperative refractive outcomes in a consecutive series of 1537 patients who had uneventful bilateral phacoemulsification. In 1379 patients with bilateral data, the researchers compared the difference in axial lengths between eyes and the magnitude of postoperative anisometropia between 1.0 mm incremental groups of axial length using the longer eye as the index eye. They assessed the postoperative refraction prediction error in 1457 left eyes in similar axial length groups, the study authors wrote.

The researchers found the difference in axial length was 0.3 mm or greater in 331 patients (24%). They reported that the axial length asymmetry between eyes increased with an increase in axial length in the index eye (P<0.001). The 95th centile of the axial length difference was 0.5 mm when the longer eye was 22.0 mm or less and 4.0 mm when it was 28 mm or greater. The researchers also found an increase in postoperative anisometropia with increasing axial length (P= 0.003). The median was 0.34 D (interquartile range [IR], 0.25-1.11) when the longer eye had an axial length of less than 28.0 mm and 0.66 D (IR, 0.16-0.66) when the longer eye had an axial length of 28.0 mm or more. In left eyes, there was an increase in biometry prediction error with an increase in axial length (P= 0.006), the study authors wrote.

Source: EyeWorld News Service

Interocular axial length difference and age-related cataract Interocular axial length difference and age-related cataract
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