March 2008




Fatty acid reduces dry eye symptoms in mice



A new study suggests eye drops containing alpha-linolenic acid (ALA) significantly reduced symptoms of dry eye syndrome in mice, reported.

Three formulations of fatty acids: 0.2% ALA; 0.2% linoleic acid (an omega-6 fatty acid); and 0.01% ALA combined with 0.1% linoleic acid were tested by Reza Dana, M.D., director, Cornea Service, Massachusetts Eye and Ear Infirmary, and colleagues at the Schepens Eye Research Institute.

According to the study, some mice received once-a-day treatment with these eye drops, while other mice received none. The eyes of mice treated with ALA showed a significant reversal in epithelial damage to the cornea, the report said.

According to the news source, Dr. Dana said that the current study is a pioneer in showing the benefit of topical application of a particular fatty acid in treating the signs of dry eye syndrome at both the molecular and cellular levels.

The professor at Harvard Medical School also said that clinical studies with topical fatty acids are being planned, which, if successful, could alter the way in which dry eye is treated, according to the report.


Reported by:

EyeWorld News Service

Fatty acid reduces dry eye symptoms in mice Fatty acid reduces dry eye symptoms in mice
Ophthalmology News - EyeWorld Magazine
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