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  MEETING REPORTER  

2007 ASCRS Summer Refractive Meeting


by David Laber EyeWorld Staff Writer
 

Reported live from
the 2007 ASCRS Summer Refractive Meeting



Editors’ note: This Meeting Reporter contains original reporting by the EyeWorld News Team from the 2007 ASCRS Summer Refractive Meeting, Aviara. Meeting Reporter is sponsored by an unrestricted grant from Advanced Medical Optics (AMO).

 
























The 2007 ASCRS Summer Refractive meeting, was held this year, north of San Diego, at the Aviara Resort, and began, Thursday, Aug. 2, with discussions of detailed statistics and vital practice management tools to assist the ophthalmic surgeon in bettering his or her practice through the coming years. Sessions were presented in an open format, encouraging attendee participation and stimulating lively discussion of practice management pearls.

Ophthalmologist predicts upcoming cataract boom as Americans age

The opportunity for ophthalmologists to expand their cataract practice will continue to improve over the next 20 years as the number of 65-year-old Americans continues to increase by two percent every year, said Richard L. Lindstrom, M.D., adjunct professor emeritus, University of Minnesota, Minneapolis. In fact, Dr. Lindstrom said some industry experts predict there will be a shortage of ophthalmologists to perform the increasing number of cataract surgeries in the next 10 to 15 years. In addition to the aging country, a combination of technological advances, consumerism and escalating costs coupled with patient-shared billing, point to a profitable future for surgeons who can perform cataract surgery. Therefore, if ophthalmologists can add refractive cataract surgery to their practice, they could enhance the practice’s net income by as much as 10% in one year and 50% over the next five years, he said.

Editors’ note: Dr. Lindstrom has no financial interests related to his presentation.

Becoming physicians again

With the current practice model failing everyone, I. Howard Fine, M.D., clinical professor, Casey Eye Institute, Oregon Health and Science University, Portland, presented changes that need to be made to create a winning situation for patients, physicians, industry and the government. Currently, ophthalmologists practice their skills in the worst possible combination—high-volume, efficient, low-cost care. Dr. Fine said the new practice model of high-quality, personalized, patient care will be a “win-win-win-win.” Patients will benefit because they will receive better care; physicians will gain greater freedom from insurance companies and government reimbursement; the industry will see a greater return on investments; and the government will benefit because it will not have to provide as much taxes for cataract reimbursement because the “Baby Boomer” population will opt for presbyopia-correcting intraocular lenses (IOLs), he said.

Editors’ note: Dr. Fine has no financial interests related to his presentation.

Necessary steps to adapt practices for better patient care

Samuel Masket, M.D., clinical professor, Jules Stein Eye Institute, University of California, Los Angeles, followed Dr. Fine’s presentation by providing six steps to improve practices. The first of the six steps, prepared by Stephen S. Lane, M.D., adjunct professor, University of Minnesota, Minneapolis, is to create an office environment that promotes internal marketing, Dr. Masket said. Then, every office employee needs to be educated as to what the office goals are. The third step is to educate patients before they arrive with brochures and Web sites such as the new ASCRS presbyopia Web site, www.readclearlyagain.org, but Dr. Masket differed slightly from Dr. Lane by adding that patients should be educated only to the extent that it will not require additional chair time to explain why they are not candidates for some procedures. The next step is for someone in the office to assess the patient’s physical candidacy, which includes the patient’s personal vision preferences. Dr. Lane included slides about how the IOL Counselor (Patient Education Concepts, Houston, Texas, in partnership with Eyeland Design Network, Germany) is a helpful tool for patients to determine their vision preferences, but Dr. Masket said he does not use it because he prefers to undersell technology. The fifth step is for the physician to diagnose and counsel the patient. Finally, Dr. Masket recommended the office staff schedule and finalize appointments and provide fee explanations.

Editors’ note: Dr. Masket has no financial interests related to his presentation.

Consider enhancements post-presbyopic surgery for successful procedure

There are five A’s to consider with presbyopic intraocular lens (IOL) selection, Dr. Masket said, but enhancements need to be used as well. The five A’s are astigmatism control, accurate biometry, appropriate formulae, adjusting for outcome and asphericity. But after those considerations, enhancements are a salient part of the visual rehabilitation of the presbyopic patient, Dr. Masket said pointing to his personal rate of 10% of his presbyopic patients. He also noted that the rate is more than likely at least 20% for most ophthalmologists. In his own practice, Dr. Masket said all enhancements he performed resulted in improved uncorrected visual acuity (UCVA), and all enhanced cases achieved spectacle independence in patients with bilateral ReSTOR IOLs (Alcon, Fort Worth, Texas). Dr. Masket also said that all of his enhancement cases also achieved at least 20/25 and J2.

Editors’ note: Dr. Masket has financial interests with Alcon (Fort Worth, Texas).

Pearls for improving office Web site

About 113 million Americans use the Internet to search for health-related topics or information, said Ray Isco, senior account manager, Mojo Interactive, Orlando, Fla. To help ophthalmologists better prepare to inform these Internet users, Mr. Isco provided several tips about Web site content. First, the Web page should have strong headlines and interesting lead paragraphs that sell services and avoid providing too much biographical information, or as Mr. Isco referred to it, “we” sentences. In contrast, the information should be “you” language as in what benefits patients will enjoy after undergoing the procedure. Information on the Web site also should set the practice apart from the competition. The information should be presented in an informal, conversational style that uses simple language that everyone understands, and it should be presented in the inverted pyramid format, which is putting all of the most important information on the top of the page and the less important on the bottom. To improve the Web site’s search engine optimization (SEO), Mr. Isco said to update the site at least two to four times per year and to keep out-of-date information off the page.

Editors’ note: Mr. Isco is an employee of Mojo Interactive (Orlando, Fla.).

Friday, Aug. 3, sessions were focused on PRK and other refractive procedures, a continued dialogue on intraocular lenses (IOLs) as well as malpractice claim statistics from one insurance provider. And as part of the Summer Refractive Congress’ tradition, many of the presentations were case reports offering attendees the opportunity to interact with the faculty.

PRK dominates second day of discussion

While the general public may recoil at the pain and length of recovery associated with PRK, Lt. Col. Scott D. Barnes, M.D., chief of ophthalmology and refractive surgery services, Fort Bragg, N.C., explained why the U.S. Army prefers PRK to other refractive procedures. For the military, the problems with LASIK include the potential for flap dislocation, buttonholes, epithelial ingrowth and diffuse lamellar keratitis, and partial cuts, Dr. Barnes said. At Fort Bragg, Dr. Barnes reported five dislocated flaps for a rate of one in every 500 cases. He also said there were two cases of dislocated flaps in Iraq resulting in one soldier being sent back to the States for treatment. Dr. Barnes said the current approach to refraction is to perform PRK on patients with less than 4 D and to perform LASEK on patients with more than –4 D. While he does not use nonsteroidal anti-inflammatory drugs (NSAIDs) or mitomycin C (MMC), but he does use antibiotics, steroids, artificial tears, Percocet (acetaminophen and oxycodone, Endo Pharmaceuticals, Chadds Ford, Pa.), vitamin C and bandage contact lenses (BCL). Simon P. Holland, M.D., clinical professor, University of British Columbia, Vancouver, provided details of a patient who did not heal after PRK. In the 26-year-old woman, one eye did heal, but the other one did not and at three weeks post-op, she was showing a 6 mm defect, Dr. Holland said. He treated her with Zovirax (acyclovir, GlaxoSmithKline, Middlesex, U.K.) and Viroptic (trifluridine, GlaxoSmithKline) after determining she had herpes simplex virus (HSV) keratitis. After she healed, an HSV scar formed, and Dr. Holland said he used phototherapeutic keratectomy (PTK) with MMC. He suggested that perhaps physicians should consider using questions about HSV and cold sores as screening questions for PRK because HSV is a potential cause of unilateral delayed epithelialization following PRK surgery.

Editors’ note: Neither Dr. Barnes nor Dr. Holland has financial interests related to his comments.

Physicians discuss malpractice concerns

James J. Salz, M.D., clinical professor, University of Southern California, Los Angeles, provided attendees with statistics from Ophthalmic Mutual Insurance Company’s (OMIC, San Francisco) malpractice claims. Dr. Salz noted that between 1993 and 2006, malpractice claims more than tripled for OMIC with the average cost per claim totaling about $50,000. With malpractice claims—despite a positive or negative outcome, the physicians will take a financial hit as Dr. Salz showed data that the average indemnity in 2006 for OMIC was $29,823 and the average expense for attorneys, experts, etc., was $24,600. The common misconception is that LASIK malpractice cases were most prevalent; however, Dr. Salz reported that cataract cases had more malpractice claims than LASIK and that this trend has been consistent at least since 2002. In fact, LASIK malpractice claims peaked in 2002 at 55 claims and had progressively declined through 2005. However, there has been a slight up-turn in 2006. Dr. Salz said the average settlements since 2003 has been comparable for LASIK and cataract cases (at about $120,000) with oculoplastics having the highest average rate (about $220,000) for OMIC.
The faculty and attendees continued the discussion by evaluating a clinical case presented by Parag A. Majmudar, M.D., associate professor, Rush University, Chicago, and how much information should be provided to the patient when a mistake is made. In the provided example, a physician began performing LASIK on a 36-year-old man with –6 D, but was treating the peripheral cornea instead and had completed 60% of the surgery before realizing the mistake. Dr. Majmudar concluded that deceiving the patient is harder to defend in a malpractice claim and therefore, the physician should be upfront with patients when a mistake is made. Dr. Salz agreed relaying a similar story in which he corrected the mistake, and even though the patient still sued the practice, the patient did not suffer any real damages and received little money in the settlement. Speaking from the audience, Marguerite B. McDonald, M.D., clinical professor of ophthalmology, Tulane University, New Orleans, and in private practice, Lynbrook, N.Y., suggested that physicians provide the essence of what went wrong without providing the exact details of what course of action led to the mistake.

Editors’ note: Dr. Majmudar has a financial interest with Advanced Medical Optics (AMO, Santa Ana, Calif.), Allergan (Irvine, Calif.) and Inspire Pharmaceuticals (Durham, N.C.). Dr. McDonald has financial interests with AMO, Alimera Sciences (Alpharetta, Ga.), Allergan, Refractec (Irvine, Calif.) and Santen Pharmaceuticals (Napa, Calif.). Dr. Salz has a financial interest with OMIC (San Francisco).

IOL conversation spills into second day of meeting

Despite spending the first day of sessions discussing patient cases dealing with intraocular lenses (IOLs), the faculty continued the discussion to a lesser degree on Friday. Jack T. Holladay, M.D., M.S.E.E., clinical professor, Baylor College of Medicine, Houston, commenced with tips on achieving accurate IOL calculations. Dr. Holladay gave five pearls to attendees: 1) attain accurate biometry, 2) attain accurate, repeatable keratometry, 3) use fourth generation formulas that take into consideration white-to-white (WTW), 4) personalize the lens constant and do not use the manufacturer’s, and 5) eliminate corneal astigmatism through LASIK, piggybacks, limbal relaxing incisions (LRIs), etc. James J. Salz, M.D., clinical professor, University of Southern California, Los Angeles, furthered the discussion by citing a clinical case of a late complication with piggyback IOLs. Dr. Salz suggested surgeons should perform a surgical peripheral iridectomy for high hyperopes with axial lengths less than 20 mm. However, even with this procedure, there still is a risk for developing “malignant glaucoma.” If such is the case, a posterior core vitrectomy and visco-dissection or a tube shunt likely may be needed to deepen the anterior chamber.

Editors’ note: Dr. Holladay has financial interests with Advanced Medical Optics (AMO, Santa Ana, Calif.), Nidek (Fremont, Calif.) and Oculus Innovative Sciences (Petaluma, Calif.). Dr. Salz has no financial interests related to his comments.

Saturday, Aug. 4, the faculty not only compared and contrasted surface ablation to LASIK and evaluated additional refractive strategies but also discussed how to identify complications pre-operatively such as ectasia and keratoconus through keynote addresses and clinical cases.

Picking optimal refractive procedure

Capt. Steve C. Schallhorn, M.D., former director of cornea and refractive surgery, Naval Medical Center, San Diego, and ASCRS Summer Refractive Congress program committee member, talked about how he chooses which procedure to use—LASIK or PRK. The problem with PRK is that it can be painful with longer recovery time, and one of the problems with LASIK is the possibility of developing ectasia, Dr. Schallhorn said. So he and his colleagues designed a study of 290 patients and looked at the results at three months post-LASIK and post-PRK. Dr. Schallhorn said the uncorrected visual acuity (UCVA) was comparable, though LASIK had a better percentage of 20/12.5 and 20/16 patients. As for best-corrected visual acuity (BCVA), most patients either had no loss or gained one line. In the end, Dr. Schallhorn determined there was not a significant difference in visual results to choose between the two procedures. LASIK has the better visual recovery time and a slightly better UCVA at three months post-op, but with PRK there is no need to make nomogram adjustments.
Dongho Lee, M.D, Ph.D., Seoul, South Korea, talked about the off-label use of mitomycin C (MMC) in surface ablation to treat corneal haze after PRK, LASEK and RK and in complicated LASIK cases. Dr. Lee and his colleagues looked at 115 eyes of 59 patients and most patients gained at least one line post-op BCVA, and most of the remaining patients did not lose or gain any lines. Six eyes (5%) did develop corneal haze, and they were enhanced through phototherapeutic keratectomy (PTK) to remove the epithelial tissue and PRK worked to decrease the haze, Dr. Lee said. Dr. Lee added that PRK with intra-operative MMC is a safe procedure to prevent corneal haze.
Noting that both surface ablation and LASIK have their drawbacks, Jason E. Stahl, M.D., assistant clinical professor, Kansas University Medical Center, Kansas City, talked about another option—sub-Bowman’s keratomileusis (SBK). SBK has the advantages of the other procedures, Dr. Stahl said, such as the fast recovery of LASIK without the risk of pain or haze while having biomechanical changes and tear function post-op similar to PRK. With femtosecond lasers creating thin, uniform flaps with high predictability and reproducibility, surgeons can achieve the optimal SBK flap, which Dr. Stahl said is highly dependent on visual axis centration.

Editors’ note: None of the presenting physicians has financial interests related to his presentation.

Pearls for identifying keratoconus

Identifying keratoconus can be difficult, but forme fruste keratoconus (FFKC) is even more difficult. David Rex Hamilton, M.D., M.S., director, University of California Los Angeles Laser Refractive Center, Jules Stein Eye Institute, Los Angeles, discussed using advanced topography and biomechanical measurements for keratoconus detection, and Stephen D. Klyce, Ph.D., professor, Tulane University, New Orleans, addressed how to effectively screen for FFKC. Dr. Hamilton said anterior corneal signs for keratoconus include steep keratometry (greater than 47 D) and irregular astigmatism such as a skewed radial axis, asymmetric bowtie and inferior steepening. But there currently are not posterior corneal signs for FFKC, he said, even though such information might be useful. In particular, Dr. Hamilton said corneal hysteresis measurements could provide diagnostic data complimentary to topographic data. Even so, there is no single parameter that can be used to diagnose FFKC, he said and all patients should understand the risk prior to surgery. Dr. Klyce said he looked at corneal topography and wavefront analysis as pre-screening tools and determined they can be used effectively to properly screen refractive surgical candidates and to understand the source of induced visual symptoms. Some pearls Dr. Klyce gave attendees regarding these tools is that normal corneal topography should have smooth color map contours, simulated keratometry of 42.75 ± 1.6 D and a symmetrical bow tie pattern. Ophthalmologists should be suspicious of corneas with central cornea thickness (CCT) less than 500 microns and look for signs of unusual peripheral thinning, he said.

Editors’ note: Dr. Hamilton has financial interests with Alcon (Fort Worth, Texas), Allergan (Irvine, Calif.) and Reichert (Depew, N.Y.). Dr. Klyce has a financial interest with Nidek (Fremont, Calif.).

Looking out for ectasia

Ectasia is not just associated with LASIK, said Ella Faktorovich, M.D., San Francisco, who noted that corneal ectasia may develop after PRK. However, she also cautioned against making the same mistake she made by jumping to the ectasia diagnosis too quickly when it could just be an irregular cornea following an irregular ablation. To screen for patients who could develop ectasia post-PRK, Dr. Faktorovich suggested that ocular allergies could be an indicator for corneal irregularities. In post-corneal refractive surgery patients, ocular allergies might need to be managed promptly and aggressively to avoid possible effects on the cornea, she said. J. Bradley Randelman, M.D., assistant professor, Emory University School of Medicine, Atlanta, provided a clinical case to discuss how to pre-operatively identify patients at risk of ectasia. Risk factors include topographic abnormalities, low residual stromal bed thickness, age (younger patients), low pre-op corneal thickness and high myopia, Dr. Randelman said. Screening for these factors might be more sensitive to the development of ectasia than the current screening strategies that rely on individual variables, he said. However, Dr. Randelman added that ectasia can develop without any of the risk factors.

Editors’ note: Dr. Faktorovich does not have any financial interests related to her comments.. Dr. Randelman has financial interests with Alcon (Fort Worth, Texas), Allergan (Irvine, Calif.) and Ista Pharmaceuticals (Irvine, Calif.).

Sunday, the final day of keynote lectures and clinical case presentations was dedicated to addressing ectasia and post-op astigmatism.

Intracorneal rings and tips for tackling ectasia

By knowing some of the risk factors associated with ectasia, an ophthalmologist may be able to avoid the development of this complication in some cases. Neal A. Sher, M.D., adjunct clinical professor of ophthalmology, University of Minnesota, Minneapolis, said some of the known risk factors of ectasia are pre-op pachymetry of less than 500 microns, a calculated residual bed of less than 250 microns, steep corneas, high attempted correction, pre-op keratoconus, deep initial flap and multiple retreats. To avoid iatrogenic keratectasia, Dr. Sher said measuring intra-operative pachymetry and deciding to cancel the procedure if the flap is too thick is one pearl. Another is for a practice to perform an increased number of surface ablations over LASIK. For LASIK procedures, he said to use a low threshold to define abnormal topography and posterior float. Finally, he suggested trying out other modalities such as the Ocular Response Analyzer (ORA, Reichert, Depew, N.Y.). Elizabeth A. Davis, M.D., adjunct clinical assistant professor, University of Minnesota, Minneapolis, and ASCRS Summer Refractive Congress program committee member, discussed using intracorneal rings (Intacs, Addition Technology, Des Plaines, Ill.) for ectasia patients. Intracorneal rings are effective for the treatment of some cases of ectasia, Dr. Davis said. She suggested trying single or double segments of varying diameters to achieve the best effect. If the intracorneal rings are not successful alone, Dr. Davis recommended the use conductive keratoplasty (CK) for enhancement. In addition to Dr. Davis’ advice about intracorneal rings, Yaron Rabinowitz, M.D., clinical professor, University of California Los Angeles School of Medicine, Los Angeles, provided additional pearls. Dr. Rabinowitz advised surgeons to ensure the intracorneal ring bisects the thinnest part of the cornea. He also recommended trying to remove the upper ring—when using two intracorneal rings—to see if the patient experiences an improved astigmatic effect. Another option is to consider recutting the channel closer to the visual axis and reinserting the intracorneal ring or making the channels more narrow with a femtosecond laser to get more effect. Finally, if all else fails, Dr. Rabinowitz said to consider penetrating keratoplasty (PKP) or IntraLase (Advanced Medical Optics, Santa Ana, Calif.)-enabled keratoplasty (IEK).

Editors’ note: Dr. Sher has financial interests with Advanced Medical Optics (AMO, Santa Ana, Calif.), Einstein Industries (San Diego) and Ista Pharmaceuticals. Dr. Davis has financial interests with AMO, Allergan (Irvine, Calif.), Bausch & Lomb (Rochester, N.Y.), IntraLase (AMO, Santa Ana, Calif.), Ista Pharmaceuticals (Irvine, Calif.), Refractec (Durham, N.C.), among other companies. Dr. Rabinowitz has no financial interests related to his comments.

Taking proper steps to manage astigmatism

Minimal astigmatism is required for optimal uncorrected vision, James J. Salz, M.D., clinical professor, University of Southern California, Los Angeles, said when delivering a presentation prepared by Douglas D. Koch, M.D., professor and the Allen, Mosbacher, and Law Chair in Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston. The key is to thoroughly plan the procedure pre-operatively, being consistent with the surgical technique and adequately managing the post-op period. During the pre-op planning, Dr. Salz said to quantify the astigmatism using one of several tools such as manual keratometry, an automated K modality such as IOL Master (Carl Zeiss Meditec, Jena, Germany/Dublin, Calif.) or topography, but to not use simulated K’s. Also during the pre-op planning, Dr. Salz advised determining the symmetry of the cuts, selecting a nomogram (which should initially match the instrumentation), identifying the site of the incision and accounting for rotation from upright to supine positions. Alignment is a key issue, Dr. Salz said because all rotational misalignments cause axis shifts. Alignment should also be done intra-operatively as part of the surgical technique and the incision made in the clear cornea, he said. Depending on the meridian of the astigmatism, the incision may intersect paracentesis incisions, which is best to avoid because they are more prone to leakage. Therefore, the surgeon should make the paracentesis incisions more centrally to avoid this potential complication. If making only one peripheral corneal relaxing incision (PCRI), Dr. Salz said to make it nasally, and if the nomogram calls for two PCRIs, make the second one temporally. During the post-op management, if the patient has been under-corrected, the ophthalmologist can lengthen the incisions or make new incisions more centrally. On the other hand, if the patient was over-corrected, the surgeon should make new incisions along the new steep meridian. Some other strategies for minimizing post-op astigmatism Dr. Salz addressed was to minimize (or correct) the astigmatism at the time of surgery, which, he added, is almost always preferable. Additionally, the surgeon could correct post-operatively by treating the residual cylinder and sphere and waiting for the refraction and topography to stabilize. Dr. Salz concluded that astigmatism management is crucial to success, especially when implanting presbyopia-correcting intraocular lenses (IOLs).

Editors’ note: Dr. Salz has no financial interests related to his comments. Dr. Koch has financial interests with Alcon Laboratories (Fort Worth, Texas) and Advanced Medical Optics (Santa Ana, Calif.).







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